منابع مشابه
Local Anesthetics Properties of Local Anesthetics
The first clinical uses of a local anesthetic agent occurred in 1884, when cocaine was employed as a topical agent for eye surgery and to produce a nerve block. These events inaugurated a new era, that of regional anesthesia. New applications were developed, including spinal, epidural, and caudal anesthesia. The search for a better local anesthetic led to chemical synthesis of a number of other...
متن کاملLocal anesthetics: review of pharmacological considerations.
Local anesthetics have an impressive history of efficacy and safety in medical and dental practice. Their use is so routine, and adverse effects are so infrequent, that providers may understandably overlook many of their pharmacotherapeutic principles. The purpose of this continuing education article is to provide a review and update of essential pharmacology for the various local anesthetic fo...
متن کاملLocal anesthetics as antimicrobial agents: a review.
BACKGROUND Since the introduction of cocaine in 1884, local anesthetics have been used as a mainstay of pain management. However, numerous studies over the past several decades have elucidated the supplemental role of local anesthetics as antimicrobial agents. In addition to their anesthetic properties, medications such as bupivacaine and lidocaine have been shown to exhibit bacteriostatic, bac...
متن کاملChapter 11 - Local Anesthetics
QUESTIONS OF THE DAY L ocal anesthesia can be defined as loss of sensation in a discrete region of the body caused by disruption of impulse generation or propagation. Local anesthesia can be produced by various chemical and physical means. However, in routine clinical practice, local anesthesia is produced by a narrow class of compounds, and recovery is normally spontaneous, predictable, and co...
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ژورنال
عنوان ژورنال: Anaesthesia and Intensive Care
سال: 1994
ISSN: 0310-057X,1448-0271
DOI: 10.1177/0310057x9402200530